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CVE-2026-54604

OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1

CVSS 4.0 5.3 MEDIUMCheck source for fixed versionsKEV status unknown
Original advisory

Historical advisory recorded 23 Oct 2026 15:48:27 UTC. Read the latest advisory.

cve-program · CVE-2026-54604

Published

OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.

Read the publisher's advisory

Affected versions, risk and source history

cve-program · CVE-2026-54604

Published

OpenSlide: openslide_read_region() returns uninitialized memory with libtiff 4.7.1

OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.

Source published
17 Sep 2026 20:29:15 UTC
Source modified
18 Sep 2026 20:06:41 UTC
Saved here
23 Oct 2026 15:48:27 UTC
Source terms
CVE Program Terms of Use

Original source record · Cite this exact observation · Complete original publisher JSON

Source: cve-program · CVE Program Terms of Use. The publisher's wording is preserved. ChangeIntel groups the information and labels changes. The JSON record includes additional source fields.

CVSS 4.0 · 5.3 CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N

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